题目：TMEDA-enabled regioselective sulfenylation of unprotected N-heterocycles via electrochemical sulfinyl radical generation

作者：Qiang Zhong（钟强，2021级研究生）, Xinru Jiang, Hui Gao*（高慧）, Pei-Long Wang and Hongji Li*（李洪基）

单位：Key Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education; Anhui Provincial Key Laboratory of Synthetic Chemistry and Applications; College of Chemistry and Materials Science, Huaibei Normal University, Huaibei, Anhui 235000, P.R. China.

摘要：An electrochemical sulfenylation of unprotected N-heterocycles with a wide range of commercially available arylsulfonyl chlorides was developed. This protocol features the use of inexpensive N,N,N’,N’-tetramethylethylenediamine (TMEDA) serving as both a promoter and a base to tune the sulfenylation process, thus affording sulfenylated products in good yields with high regioselectivity. Importantly, TMEDA significantly lowers the oxidation potential of indole, thus avoiding the over-oxidation of indole.

影响因子：4.6

分区情况：一区

链接: https://doi-org.2421.top/10.1039/D4QO01772B

（文：李洪基 / 审核：韩满意 / 审校：曹静 / 终审：杨振兴）