基础信息

姓    名：  鲁神赐      职  称: 教授   政治面貌：民盟   

工作单位：淮北师范大学化学与材料科学学院

Email: lushenci@chnu.edu.cn

科学研究

主要研究方向：有机不对称催化，迄今以第一作者或通讯作者发表J. Am. Chem. Soc. (1篇),  Nat. Commun. (2篇), Angew. Chem. Int. Ed. (5篇), ACS Catal. (2篇)，Chem. Sci. (1篇), Org. Lett. (5篇), Org. Chem. Front., Chin. J. Chem. (2篇) 等国际著名期刊上发表研究性论文20余篇。

教育背景

2001.09–2005.06  黄冈师范学院    化学专业   理学学士

2005.09–2008.06   兰州大学     有机化学专业 理学硕士

2008.09–2011.06   兰州大学     有机化学专业 理学博士

工作经历

2011.10–2018.10  新加坡国立大学    理学院化学系    博士后

2018.11–2025.3   西北工业大学     柔性电子研究院    教授

2025.3–今      淮北师范大学   化学与材料科学学院   教授

奖励荣誉

1. 2020年获得“陕西省高层次青年人才”

2. 2022年获得西北工业大学优秀硕士学位论文指导教师

3. 2023年获得“Thieme Chemistry Journal Award” 国际(德国)学术奖

4. 2024年获得Chinese Journal of Chemistry年度新锐科学家奖

代表性论文

1. Shao-Jie Wang, Xia Wang, Xiaolan Xin, Shulei Zhang, Hui Yang, Ming Wah Wong,* Shenci Lu.* Organocatalytic diastereo- and atroposelective construction of N–N axially chiral pyrroles and indoles. Nat. Commun. 2024, 15, 518. (ESI高被引论文&热点论文)

2. Jianfeng Jiang, Xia Wang, Shengping Liu, Sichen Zhang, Binmiao Yang, Yu Zhao, Shenci Lu.* Enantioselective Cascade Annulation of α-Amino-ynones and Enals Enabled by Gold and Oxidative NHC Relay Catalysis. Angew. Chem. Int. Ed. 2022, 61, e202115464. (Highlighted by Synfacts 2022, 18, 610)

3. Shenci Lu, Shawn Voon Hwee Ng, Kaitlyn Lovato, Jun-Yang Ong, Si Bei Poh, Xiao Qian Ng, László Kürti,* Yu Zhao.* Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation. Nat. Commun. 2019, 10, 3061. 

4. Shenci Lu, Jun-Yang Ong, Hui Yang, Si Bei Poh, Xi Liew, Chwee San Deborah Seow, Ming Wah Wong,* Yu Zhao.* Diastereo- and Atroposelective Synthesis of Bridged Biaryls Bearing an Eight-Membered Lactone through an Organocatalytic Cascade. J. Am. Chem. Soc. 2019, 141, 17062-17067. 

5. Shulei Zhang, Shao-Jie Wang, Xiaolan Xin, Xia Wang, Zhifeng Tu,* Shenci Lu.* Diastereo- and Enantioselective Chemodivergent Three-Component Cascade Reactions via Gold and Carbene Sequential Catalysis. ACS Catal. 2024, 14, 9275-9282.

6. Si-Chen Zhang, Shengping Liu, Xia Wang, Shao-Jie Wang, Hui Yang, Lin Li, Binmiao Yang, Ming Wah Wong,* Yu Zhao, Shenci Lu*, Enantioselective Access to Triaryl-2-pyrones with Monoaxial or Contiguous C-C Diaxes via Oxidative NHC Catalysis. ACS Catal. 2023, 13, 2565-2575. (ESI高被引论文）

7. Xia Wang, Shao-Jie Wang, Xiaolan Xin, Hao An, Zhifeng Tu*, Hui Yang, Ming Wah Wong,* Shenci Lu.* Enantioconvergent and Diastereoselective Synthesis of Atropisomeric Hydrazides Bearing a Cyclic Quaternary Stereocenter through Ternary Catalysis. Chem. Sci. 2024, 15, 13240-13249.

8. Si Bei Poh, Jun-Yang Ong, Shenci Lu,* Yu Zhao.* Highly Regio- and Stereodivergent Access to 1,2-Amino Alcohols or 1,4-Fluoro Alcohols by NHC-Catalyzed Ring Opening of Epoxy enals. Angew. Chem. Int. Ed. 2018, 57, 1645-1649. 

9. Shenci Lu,# Jun-Yang Ong,# Si Bei Poh, Terence Tsang, Yu Zhao.* Transition Metal-Free Decarboxylative Propargylic Substitution/ Cascade Cyclization with Azolium Enolates or Acyl Anions. Angew. Chem. Int. Ed. 2018, 57, 5714-5719.

10.  Shenci Lu, Si Bei Poh, Yu Zhao.* Kinetic Resolution of 1,1’-Biaryl-2,2’-Diols and Amino Alcohols through NHC-Catalyzed Atroposelective. Angew. Chem. Int. Ed. 2014, 53, 11041-11045. 

11. Shenci Lu, Si Bei Poh, Woon-Yew Siau, Yu Zhao.* Kinetic Resolution of Tertiary Alcohols: Highly Enantioselective Access to 3-Hydroxy-3-Substituted Oxindoles. Angew. Chem. Int. Ed. 2013, 52, 1731-1734. 

12. Xiaoyi Yu, Hao An, Wenbin Wu, Fei Xue, Yina Jiang, Siew Yin Chan, Zhifeng Tu,* Shenci Lu.* Enantioselective Cascade Annulation of 1,2,3-triazoles and Enals Enabled by Sequential Rhodium and Oxidative NHC Catalysis Involving Cleavage, Migration, and Cyclization. Org. Lett. 2025, 27, 2383-2388. (Highlighted by Synfacts 2025, 21, 483)

13. Hao An, Shifei Liu, Shao-Jie Wang, Xiaoyi Yu, Chenqi Shi, Haonan Lin, Si Bei Poh, Hui Yang, Ming Wah Wong, Yu Zhao, Zhifeng Tu,* Shenci Lu.* Kinetic Resolution of Acyclic Tertiary Propargylic Alcohols by NHC Catalyzed Enantioselective Acylation. Org. Lett. 2024, 26, 702-707.

14. Dan Hu, Si Bei Poh, Feipeng Liu, Zhifeng Tu, Xi Wang, Shenci Lu,* Yu Zhao.*Anion effect on enantioselective oxidative NHC catalysis: highly efficient kinetic resolution of tertiary alcohols and beyond. Org. Chem. Front. 2023, 10, 416-421.

15. Xi Wang, Shulei Zhang, Shao-Jie Wang, Hao An, Xiaolan Xin, Haonan Lin, Zhifeng Tu,* Shenci Lu.* An Assembly of Pyrano[3,2-b]indol-2-ones via NHC-Catalyzed [3 + 3] Annulation of Indolin-3-ones with Ynals. Chin. J. Chem. 2024, 42, 1487-1492.

16. Lingzi Zhao, Xuchao Wang, Qing Qiang, Xingwei Zhao, Feipeng Liu,* Shenci Lu,* Zi-Qiang Rong.* Ruthenium-Catalysed Asymmetric Intramolecular Isomerization/Esterification Reaction: Direct Synthesis of Chiral Dihydrocoumarins. Chin. J. Chem. 2024, 42, 1828-1832.

17. Jun-Yang Ong, Xiao Qian Ng, Shenci Lu,* Yu Zhao.* Isothiourea-Catalyzed Atroposelective N‑Acylation of Sulfonamides. Org. Lett. 2020, 22, 6447-6451.

18. Shenci Lu, Si Bei Poh, Zi-Qiang Rong,* Yu Zhao.* NHC-Catalyzed Atroposelective Acylation of Phenols: Access to Enantiopure NOBIN Analogs by Desymmetrization. Org. Lett. 2019, 21, 6169-6172.

出版、撰写的学术专著、专业教材

1. Shenci Lu, Si B. Poh, Jun Y. Ong, Yu Zhao. N-Heterocyclic Carbenes in Organocatalysis. Chapter 10, NHC-Catalyzed Kinetic Resolution, Desymmetrization, and DKR Strategies. pg 287-308 Published 2019 byWiley-VCH Verlag GmbH & Co. KGaA. 专著章节