题目：Photoinduced boryl-oximation of alkenes via NHC-boryl radical generation

作者：Qiang Huang^*(黄强), Na Li, Panke Zhang, Hongji Li^*(李洪基)

单位：Key Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education; Anhui Provincial Key Laboratory of Synthetic Chemistry and Applications; College of Chemistry and Chemical Engineering, Huaibei Normal University, Huaibei, Anhui 235000, China

摘要：Boryl-functionalization of C–C multiple bonds offers a powerful route to organoboron compounds. Traditional transition-metal-catalyzed methods face challenges such as toxic residues and poor functional group tolerance. Furthermore, the recently reported photoredox-catalyzed boryl functionalizations remain dependent on tailored photocatalysts, including Ir^III(bpy)₃, Ir^III(bpy)₂(dtbbpy)PF₆ and 4-CzIPN. N-Heterocyclic carbene (NHC) boranes, as versatile precursors, enable C–B bond formation via photochemical boryl radical generation. Herein, we describe a metal-free radical chain transfer strategy for NHC-boryl radical generation through thiol-catalyzed hydrogen atom transfer, achieving boryl-oximation of alkenes with a broad substrate scope and high selectivity. The resulting a boryloximes serve as versatile synthetic intermediates, enabling late-stage functionalization of pharmaceutical molecules and further product transformations. Mechanistic studies highlight the critical role of light irradiation in sustaining the radical process.

影响因子：7.4

分区情况：一区

年、卷、页：2025, 16, 19263-19270.

链接：https://pubs.rsc.org/en/content/articlelanding/2025/sc/d5sc03708e

（文、图：黄强 /     审核：刘理华 /     审校：孟令国 /     终审：赵娟）